"Leading With My Heart" was featured on the soundtrack for the film Win a Date with Tad Hamilton!.
The song was featured in the films How to Deal, 13 Going on 30, and Win a Date with Tad Hamilton! It was also featured in the television series The O.C. and in the tenth season promo for Friends.
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The Barry White recording was featured in the films Cookie (1989), Win a Date with Tad Hamilton! (2004), Robots (2005), and 16 Blocks (2006), where the song appeared on the soundtrack and, in the film, was heard during the closing credits.