The northern and western portions of the park are somewhat more remote, but can be reached from Interstate 81, NY 3, NY 28, and US 11.
Interstate 81 crosses its northern tier and interchanges with 11/15 in Summerdale.
The East Side can be defined as encompassing the area north of the Susquehanna River, east of the Brandywine Highway (NY-7), downtown and the North Side, west of the town of Kirkwood and south of the Quickway, (NY-17)/(I-81).
Georgetown occupies most of the southwestern half of Wilkes-Barre Township and is bisected by Interstate 81/Pennsylvania Route 309.
Gray lies just outside the junction between Interstate 81 and Interstate 26, the latter of which runs directly through the town.
The former connects Interstate 81 in the southeast with Route 11 in West Nanticoke, while the latter two connect Wilkes-Barre and Nanticoke.
Jonesborough is centered around the junction of Andrew Johnson Highway (which is part of both U.S. Route 321 and U.S. Route 11), which connects the town to Greeneville to the southwest and Johnson City to the northeast, and Tennessee State Route 81, which connects Jonesborough to Interstate 81 to the northwest and Interstate 26 at Erwin to the southeast.
It is located in Union Township and Route 72 has its northern terminus there at its interchange with Interstate 81.
Route 39 passes east-to-west through the village, is designated Linglestown Road, and connects Interstate 81 with Highway 22-322 to the west.
Route 81 forms the neighborhood's boundary to the west, in the south it is roughly marked by Seneca Turnpike as it ascends from The Valley, in the east by (from north to south) Comstock Ave., East Colvin St.
On July 23, 2009, brothers Stone Weeks, 24, and Holt Weeks, 20, both students at Rice University, were killed on Interstate 81 in Shenandoah County, Virginia, when a tractor-trailer truck struck their car, resulting in a multi-vehicle collision.
The Thousand Islands Bridge connects New York State and Ontario by traversing Wellesley Island at the northernmost point of Interstate 81 in Jefferson County and meets Highway 137, which leads to Highway 401.
From its headwaters near Interstate 81, the river flows southeast through several water gaps in the Ridge-and-Valley Appalachians, ending at its confluence with the Schuylkill River in Schuylkill Haven.
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The West Branch's source is several small ponds east of Interstate 81, near the small community of Buck Run.
Just east of West Nanticoke, Route 29 becomes the South Cross Valley Expressway, crossing the Susquehanna River and leading to Interstate 81 south of Wilkes-Barre.
It is crossed from northeast to southwest by Interstate 81/Route 309 and Business Route 309 (Wilkes-Barre Township Boulevard).
Since the end of the dynasty in 2005, the Typhoon have struggled to maintain their winning tradition with many of their players moving to different teams including Interstate 81 rival Harrisburg Lunatics.
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Most Residents in Baileyton work in Greeneville or other nearby Cities, There are several Restaurants and Gas Stations off Interstate 81 exit 36.
Because of its central location between Martinsburg and Winchester, Virginia along Interstate 81 and U.S. Highway 11, Bunker Hill has experienced a period of residential growth beginning in the 1980s and continuing into the 21st century.
Several restaurants, gas stations and hotels are located at the Mosheim exit of Interstate 81, Exit 23.
It is located in the Wyoming Valley east of Interstate 81 and along Interstate 476 just south of the Wyoming Valley Interchange of the Pennsylvania Turnpike.